======================================================================================================= Welcome to use DNRLMF-MDA algorithm. DNRLMF-MDA is a novel and effective computational model for miRNA-disease association prediction. This README.txt is used to give a brief introduce for the data directory and code files included in this directory. ------------------------------------------------------------------------------------------------------- ### Author:Cheng Yan, Jianxin Wang, Peng Ni, Wei Lan and Fang-Xiang Wu ### E-mail:jxwang@mail.csu.edu.cn yancheng01@mail.csu.edu.cn ======================================================================================================= PyDNRLMF-MDA.py: the 5-fold cross validation PyDNRLMF-MDAdenovo.py: all miRNAs denovo validation PyDNRLMF-MDAdenovo50.py: ramdonly chosen 50 miRNAs denovo validation PyDNRLMF-MDAparameter.py: Finding the optimal parameters of DNRLMF-MDA ###data directory including three datasets HMDD2.0-You-disease.txt:the diseases name on HMDD2.0-You dataset HMDD2.0-You-diseasefunsim.txt: the functional similarity of diseases on HMDD2.0-You dataset HMDD2.0-You-diseasesemsim.txt: the semantic similarity of diseases on HMDD2.0-You dataset HMDD2.0-You-miRNA.txt:the miRNAs name on HMDD2.0-You dataset HMDD2.0-You-miRNA-disease.txt: the known miRNA-disease associations on HMDD2.0-You dataset, row represents miRNAs and col represents diseases HMDD2.0-Wei-disease.txt:the diseases name on HMDD2.0-Wei dataset HMDD2.0-Wei-diseasefunsim.txt: the functional similarity of diseases on HMDD2.0-Wei dataset HMDD2.0-Wei-diseasesemsim.txt: the semantic similarity of diseases on HMDD2.0-Wei dataset HMDD2.0-Wei-miRNA.txt:the miRNAs name on HMDD2.0-Wei dataset HMDD2.0-Wei-miRNA-disease.txt: the known miRNA-disease associations on HMDD2.0-Wei dataset, row represents miRNAs and col represents diseases HMDD2.0-Cheng-disease.txt:the diseases name on HMDD2.0-Cheng dataset HMDD2.0-Cheng-diseasefunsim.txt: the functional similarity of diseases on HMDD2.0-Cheng dataset HMDD2.0-Cheng-diseasesemsim.txt: the semantic similarity of diseases on HMDD2.0-Cheng dataset HMDD2.0-Cheng-miRNA.txt:the miRNAs name on HMDD2.0-Cheng dataset HMDD2.0-Cheng-miRNA-disease.txt: the known miRNA-disease associations on HMDD2.0-Cheng dataset, row represents miRNAs and col represents diseases