A fast hierarchical clustering
algorithm for functional modules discovery in protein interaction networks
Min Li, Jian-xin Wang,
Jian-er Chen, Yi Pan
School of Information Science and
Engineering, Central South University, China
Software download: HC-PIN
DataSet:
The original protein-protein
interaction data was downloaded from DIP (http://dip.doe-mbi.ucla.edu/). Each interaction
in the original protein interaction network is assigned a confidence score
based on the logisticregression scheme. The final weighted protein interaction
network used in this paper is given as Test.txt.
Additional files:
Additional file 1: Example for
hierarchical organization of functional modules.
This file contains the hierarchical modules shown in
Figure 2 which are identified by HC-PIN with different values of parameter ¦Ë.
Additional file 2: Supplementary Figure
This file contains a supplementary Figure which shows the
reduction of hierarchical structure of biological process annotations for the
hierarchical modules shown in Figure 2.
E-mail£ºlimin@mail.csu.edu.cn